2-Adamantanone oxime

Base Information

  • Chemical Name: 2-Adamantanone oxime
  • CAS No.: 4500-12-3

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1.What is the 2-Adamantanone oxime ?

Used in Pharmaceutical Industry:
2-Adamantanone oxime is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new medications with diverse therapeutic profiles.
Used in Agrochemical Industry:
2-Adamantanone oxime is utilized as an intermediate in the production of agrochemicals, indicating its potential role in the development of pesticides or other agricultural chemicals that can enhance crop protection and yield.
Used in Parkinson's Disease Treatment:
2-Adamantanone oxime is studied for its potential use as a therapeutic agent in the treatment of Parkinson's disease, highlighting its role in managing the symptoms and progression of this neurological condition.
Used in Influenza Treatment:
2-Adamantanone oxime is also considered for its potential applications in treating influenza, suggesting its antiviral properties that could be harnessed to combat the influenza virus.
Used in Antiviral Applications:
2-Adamantanone oxime has been studied for its antiviral properties, making it a candidate for further research and development in creating antiviral medications.
Used in Antiproliferative Applications:
Due to its antiproliferative properties, 2-Adamantanone oxime is explored for its potential to inhibit the proliferation of certain cells, which could be beneficial in treating conditions where uncontrolled cell growth is a concern.
Used in the Preparation of Amantadine:
2-Adamantanone oxime is used in the preparation of amantadine, a medication that is specifically used to treat Parkinson's disease and influenza A virus infections, underlining its importance in the synthesis of this specific drug.

2-Adamantanone
700-58-3

2-Adamantanone

2-adamantanone oxime
4500-12-3

2-adamantanone oxime

Conditions
Conditions Yield
With hydroxylamine hydrochloride; sodium acetate; In ethanol; at 60 ℃; for 2h;
100%
With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 20 ℃;
95%
With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; for 1h; Heating;
86%
With hydroxylamine hydrochloride; sodium hydroxide; In ethanol;
86%
With hydroxylamine hydrochloride; sodium acetate; In methanol; water; for 4h; Yield given; Heating;
With hydroxylamine hydrochloride; In pyridine; at 90 ℃; for 3h;
3.5 g
With hydroxylamine hydrochloride; sodium acetate; In water; acetonitrile; at 20 ℃; for 24h;
With hydroxylamine hydrochloride;
With hydroxylamine hydrochloride; sodium acetate trihydrate; In methanol; water;
With hydroxylamine hydrochloride; sodium acetate trihydrate; In methanol; dichloromethane; water;
With hydroxylamine hydrochloride; sodium hydroxide; In ethanol; water; at 0 - 20 ℃;
N-(2-adamantyl)amine
13074-39-0

N-(2-adamantyl)amine

2-adamantanone oxime
4500-12-3

2-adamantanone oxime

Conditions
Conditions Yield
With tungusten oxide/alumina; oxygen; 2,2-diphenyl-1-picrylhydrazine; In acetonitrile; at 80 ℃; for 48h; under 37503.8 Torr;
80 %Chromat.

2.What is the CAS number for 2-Adamantanone oxime ?

The CAS number of 2-Adamantanone oxime is 4500-12-3.

More information of 2-Adamantanone oxime 4500-12-3 are:

CAS?Number

4500-12-3

Density

1.5 g/cm3

Melting Point

164-167 °C

Boiling Point

294 °C at 760 mmHg

Flash Point

175.6 °C

Vapor Pressure

0.000409mmHg at 25°C

Refractive Index

1.752

HS CODE

29280000

PSA

32.59000

LogP

2.27270

Pka

12.46±0.20(Predicted)

3.What are another words for 2-Adamantanone oxime ?

Synonyms?for?2-Adamantanone oxime 4500-12-3:2-Adamantanone,oxime (6CI,7CI,8CI);Tricyclo[3.3.1.13,7]decanone, oxime (9CI);2-Hydroxyiminoadamantane;Adamantanone oxime;NSC 127840;2-Adamantanone oxime;

4.What is the molecular formula of 2-Adamantanone oxime?

The chemical formula of ?2-Adamantanone oxime is?C10H15NO which containing 10 Carbon atoms,15 Hydrogen atoms,1 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??2-Adamantanone oxime?is 165.235.

5.What is 2-Adamantanone oxime (4500-12-3) used for?

2-Adamantanone oxime, also known as amantadine oxime, is an organic compound with the chemical formula C10H15NO. It is a white solid with a melting point of 179-181 °C. 2-Adamantanone oxime is primarily recognized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. Its versatile chemical structure and properties have led to its exploration for potential therapeutic and biological applications, including its use in the treatment of Parkinson's disease and influenza, as well as its antiviral and antiproliferative properties.

InChI:InChI=1/C10H15NO/c12-11-10-8-2-6-1-7(4-8)5-9(10)3-6/h6-9,12H,1-5H2/b11-10-

Relevant articles related to 2-Adamantanone oxime:

Article

Source

Synthesis and biological evaluation of phenylpropanoid derivatives

Liu, Sheng,Li, Yubin,Wei, Wanxing,Wei, Jingchen

, p. 1074 - 1086 (2016/07/06)

CENTRALLY ACTIVE AND ORALLY BIOAVAILABLE ANTIDOTES FOR ORGANOPHOSPHATE EXPOSURE AND METHODS FOR MAKING AND USING THEM

-

Page/Page column 50; 51, (2014/09/03)

6.Buy 2-Adamantanone oxime with the best price .

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