LOGANIC ACID

Base Information

Quality products?make an important contribution to long-term revenue and profitability. Offer Chemical Raw Material LOGANIC ACID 22255-40-9 In Stock

1.What is the LOGANIC ACID ?

Used in Pharmaceutical Industry:
LOGANIC ACID is used as a therapeutic agent for various health conditions due to its diverse biological activities. It aids in the treatment of diabetes by stimulating glucagon-like peptide-1 (GLP-1) secretion and inhibiting adipocyte differentiation. Additionally, it serves as an anti-atherosclerotic agent, reducing the plasma atherogenic index and cardiac risk ratio in a rabbit model of atherosclerosis induced by a cholesterol-rich diet.
Used in Anti-Inflammatory Applications:
LOGANIC ACID is used as an anti-inflammatory agent, as it helps decrease the levels of IL-6, TNF-α, and oxidized LDL (oxLDL) in the plasma, contributing to the reduction of inflammation in the body.
Used in Nutritional Supplements:
Given its antidiabetic and antiadipogenic properties, LOGANIC ACID can be used as an ingredient in nutritional supplements aimed at promoting healthy blood sugar levels and preventing obesity.
Used in Research and Development:
LOGANIC ACID's diverse biological activities make it a valuable compound for research and development in the fields of pharmacology, nutrition, and medicine, as it can potentially lead to the discovery of new treatments for various health conditions.

(1S,4aS,6S,7R,7aS)-7-Methyl-6-[(E)-(3-phenyl-acryloyl)oxy]-1-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid
79636-20-7

(1S,4aS,6S,7R,7aS)-7-Methyl-6-[(E)-(3-phenyl-acryloyl)oxy]-1-((2S,3R,4S,5R,6R)-3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-1,4a,5,6,7,7a-hexahydro-cyclopenta[c]pyran-4-carboxylic acid

(E)-3-phenylacrylic acid
140-10-3

(E)-3-phenylacrylic acid

loganic acid
82509-41-9,22255-40-9

loganic acid

Conditions
Conditions Yield
With sodium hydroxide; Ambient temperature;
methanol
67-56-1

methanol

2'-(2'',3''-dihydroxybenzoyl)loganic acid

2'-(2'',3''-dihydroxybenzoyl)loganic acid

methyl-2,3-dihydroxybenzoate
2411-83-8

methyl-2,3-dihydroxybenzoate

loganic acid
82509-41-9,22255-40-9

loganic acid

Conditions
Conditions Yield
With sodium hydroxide; at 30 ℃; for 3h;
0.8 mg
1.2 mg

2.What is the CAS number for LOGANIC ACID ?

The CAS number of LOGANIC ACID is 22255-40-9.

More information of LOGANIC ACID 22255-40-9 are:

CAS?Number

22255-40-9

Density

1.6 g/cm3

Boiling Point

646.257 °C at 760 mmHg

Flash Point

235.557 °C

Vapor Pressure

1.97E-19mmHg at 25°C

Refractive Index

1.633

PSA

166.14000

LogP

-2.23920

Pka

4.55±0.70(Predicted)

3.What are another words for LOGANIC ACID ?

Synonyms?for?LOGANIC ACID 22255-40-9:Cyclopenta[c]pyran-4-carboxylic acid, 1a-(b-D-glucopyranosyloxy)-1,4aa,5,6,7,7aa-hexahydro-6a-hydroxy-7a-methyl- (8CI);Loganic acid(6CI);Acide (1S,4aS,6S,7R,7aS)-1-(β-D-glucopyranosyloxy)-6-hydroxy-7-méthyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylique;Acide (1S,4aS,6S,7R,7aS)-6-hydroxy-7-méthyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylique;(1S,4aS,6S,7R,7aS)-1-(β-D-Glucopyranosyloxy)-6-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid;(1S,4aS,6S,7R,7aS)-6-Hydroxy-7-methyl-1-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid;

4.What is the molecular formula of LOGANIC ACID?

The chemical formula of ?LOGANIC ACID is?C16 H24 O10 which containing 16 Carbon atoms,24 Hydrogen atoms and 10 Oxygen atoms,and the molecular weight of??LOGANIC ACID?is 376.361.

5.What is LOGANIC ACID (22255-40-9) used for?

Loganic acid is an iridoid glycoside that has been found in C. mas and has diverse biological activities, including antidiabetic, antiadipogenic, anti-atherosclerotic, and anti-inflammatory properties. Loganic acid (1 μM) stimulates glucagon-like peptide-1 (GLP-1) secretion by NCI H716 human enteroendocrine colorectal cancer cells. It inhibits dexamethasone-, 3-isobutyl-1-methylxanthine-, and insulin-induced differentiation of mouse 3T3-L1 fibroblasts into adipocytes when used at a concentration of 10 μg/ml. Loganic acid (20 mg/kg per day) decreases the plasma atherogenic index, a ratio of triglyceride to HDL cholesterol, and the cardiac risk ratio, a ratio of total cholesterol to HDL cholesterol, in a rabbit model of atherosclerosis induced by a cholesterol-rich diet. It also decreases IL-6, TNF-α, and oxidized LDL (oxLDL) plasma levels in the same model.

InChI:InChI=1/C16H24O10/c1-5-8(18)2-6-7(14(22)23)4-24-15(10(5)6)26-16-13(21)12(20)11(19)9(3-17)25-16/h4-6,8-13,15-21H,2-3H2,1H3,(H,22,23)

Relevant articles related to LOGANIC ACID:

Article

Source

Iridoids from Gentiana loureirii

Wu, Min,Wu, Ping,Liu, Meifang,Xie, Haihui,Jiang, Yueming,Wei, Xiaoyi

, p. 746 - 750 (2009)

7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures

Katano, Nobuyuki,Yamamoto, Hirobumi,Iio, Reiko,Inoue, Kenichiro

, p. 53 - 58 (2007/10/03)

6.Buy LOGANIC ACID with the best price .

Shijiazhuang Cordial Chemicals CO.,LTD is a quality supplier of LOGANIC ACID. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on LOGANIC ACID 22255-40-9.

Online Inquiry
*Product Name
CAS
Purity
Quantity
Company name
*Email
*Other Description
*Code
Fields with* are required